Rewritable digital data stored in live DNA
“It took us three years and 750 tries to make it work, but we finally did it,” says Jerome Bonnet, a postdoctoral scholar at Stanford University, who worked with graduate student Pakpoom Subsoontorn and assistant professor Drew Endy to reapply natural enzymes adapted from bacteria to flip specific sequences of DNA back and forth at will.
In practical terms, they have devised the genetic equivalent of a binary digit—a “bit” in data parlance. “Essentially, if the DNA section points in one direction, it’s a zero. If it points the other way, it’s a one,”
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